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Department of Otolaryngology, Head & Neck Surgery

General Description of the Department

The department conducts diagnosis, treatment, and research regarding the disorders of sensory organs involving in auditory, olfactory, and gustatory senses, voice and speech, and swallowing function. For outpatient clinic, we offer specialty clinics including a clinic for vertigo, hearing impairment, and tinnitus, a clinic for patients with hearing aids, a clinic for allergy sufferers, a clinic for disorders of olfactory sense and paranasal sinuses, and a follow-up clinic for head and neck cancer patients in addition to offering a general outpatient clinic three times a week. For treatment of inpatients, we mainly perform surgical treatment for head and neck tumor, otitis media, sinusitis, tonsillitis, and vocal cord polyp. The department also provides acute treatment for sudden deafness, Menierefs disease, facial nerve palsy, and facial trauma. We also perform nocturnal apnea monitoring to patients suspected of having sleep apnea syndrome. Our research field covers the area of allergology, tumor immunology, molecular oncology, and neurological otology.

Members of the Faculty

Keisuke Masuyama
(Professor: surgery of head and neck tumor, tumor immunology, allergology, endoscopic sinus surgery, ear surgery)
Zensei Matsuzaki
(Associate Professor: surgery of head and neck tumor, head and neck reconstructive surgery, allergology)
Atsushi Kamijo
(Assistant Professor: endoscopic sinus surgery, ear surgery, disorders of paranasal sinuses and smell, mucosal immunity)
Kazuaki Chikamatsu
(Assistant Professor: surgery of head and neck tumor, head and neck reconstructive surgery, tumor immunology, molecular oncology)
Akihito Mizukoshi
(Research Associate: ear surgery, equilibrium, neurological otology, hearing aids)
Syuichiro Endo
(Research Associate: ear surgery, infantile deafness, hearing aids)
Tomokazu Matsuoka
(Research Associate: head and neck reconstructive surgery, allergology, tumor immunology, mucosal immunology)
Goro Takahashi
(Research Associate: endoscopic sinus surgery, clinical epidemiology, allergology, disorder of smell)
Takahiro Yamanishi
(Research Associate: surgery of head and neck tumor, allergology, tumor immunology)
Atsushi Okamoto
(Research Associate: endoscopic sinus surgery, disorders of paranasal sinuses and smell, mucosal immunity)

General Description of rsearch Activities

1.We conduct basic research on a role of antigen-specific T cells in allergic inflammation to investigate into pathophysiology of allergic rhinitis. We also research on operative mechanisms of allergen-specific immunotherapy. For clinical research, we conduct annual epidemiologic studies on pollen allergies in Yamanashi Prefecture and try out intranasal corticosteroids as an initial therapy for Japanese cedar pollen-induced seasonal rhinitics.

2.We research on the secretion of nasal mucus goblet cells to control mucus secretion in the upper respiratory tract. For clinical research, we try out surgical treatment and new pharmacological agents to relieve allergic symptoms.

3.In the area of head and neck cancer, we have presented many reports on the reconstruction after head and neck cancer resection. We also conduct a phase I/II trial of chemotherapy (TPF) in advanced head and neck cancer. In addition, we try to conduct research on adoptive immunotherapy for advanced head and neck cancer. In basic research, we have clarified cancer stem cells in head and neck cancer and try to establish new therapeutic strategies against advanced head and neck cancer.

4.In neurological otology, we examine eye movement regulation by cerebellum, clinical evaluation of the Head-up Tilt Test in patients with vertigo and try out TRT for tinnitus patients. We also try to conduct research on bone conduction hearing aids.
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